The results showed that Klebsiella pneumoniae induced the production of more inflammatory cells and upregulation of inflammatory factor gene expression, while under normal light/dark (L/D) conditions, it could induce stronger inflammatory responses. The anti-inflammatory drug G6PDi-1 rescued the zebrafish inflammation caused by Klebsiella pneumoniae treatment and rescued the disrupted clock gene expression of Klebsiella pneumoniae.
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