For small sample data containing mutation data, the convergence speed of the BP neural network model becomes slower, it is easy to overfit, it is easy to fall into the local optimum, and the model prediction accuracy is reduced.For small sample data containing mutation data, the convergence speed of the BP neural network model becomes slower, it is easy to overfit, it is easy to fall into the local optimum, and the prediction accuracy of the model is reduced.For the small sample data with mutation data, the convergence speed of BP neural network model is slow, it is easy to over fit and fall into local optimum, and the prediction accuracy of the model is reduced.