The lesion has a potential and differential effect on osteoblasts, whereas for bone-breaking cells, it is inhibited, and the total amount of flavonoids can be used to inhibit bone absorption by promoting expression of osteoblast OPG and inhibiting RANKL, ie regulating the rankL-OPG ratio, regulating bone metabolism, reducing the number of bone-breaking cells and preventing differentiation of bone-breaking cells, and reducing the concentration of Ca 2-plus bone-breaking cells to enhance treatment effect osteoporosis.