HL-60 cells differentiate to neutrophils after eight days of incubation in the presence of All Transretinoic acid (ATRA). siRNAs are synthetic molecules used to suppress expression of genes. In theexperiment whose results are presented below, an siRNA against the PTEN gene was used. Annexin Vis a marker used to show apoptosis, and CD11b is a neutrophil surface marker. Percentage of apoptoticand differentiated cells as well as combination of both are shown in panels A, B and C. In panels A andB, stars indicate statistical significant.