Figure 8. Demonstration of co-localization of complement components with SARS-CoV2 spikeglycoprotein in the lung of Case 1. A: Striking deposition of C4d within the inter-alveolar septaof the lung was first demonstrated by DAB staining. Using NUANCE software the C4d imageappears green (B) while the SARS-CoV2 spike protein appears red (C). D: A merged imageshows a significant degree of C4d and SARS-CoV2 co-localization, as revealed by intenseyellow staining. E-H: A similar pattern was observed using an anti-C5b-9 reagent whose imageappears green, with a significant degree of C5b-9 and SARS-CoV2 co-localization, as revealedby intense yellow staining.