Local drug injection in the treatment of pathological scar is widely used because of its advantages of less trauma and simple operation [4]. Botulinum toxin type A, corticosteroids (including diprospan and triamcinolone acetonide (TAC)), verapamil and 5-fluorouracil (5-FU) are the main drugs for local injection in the treatment of pathological scars [5]. However, the efficacy of these four drugs in the treatment of pathological scar has not yet been determined. To help doctors choose drugs for the treatment of pathological scars better, we carried out this network meta-analysis [6]. It is hoped that our study will provide evidence for doctors to choose appropriate drugs to treat pathological scar in clinical work.