且其表达水平与患者TNM分期、术后复发和转移显著相关。Kaplan-M

And its expression levels in patients with TNM stage was significantly associated postoperative recurrence and metastasis. Kaplan-Meier survival analysis showed that: high expression of overall survival after LINC00511 patients was significantly lower than patients with low expression, consistent with the TCGA database results. Preliminary results show that the above: LINC00511 tumor promoters may affect as factors of HCC, development and prognosis, and can be used as radical after hepatectomy novel prognostic marker candidates. <BR>To clarify the relationship LINC00511 with HCC biological function, we constructed a model of liver cancer cells transiently silence LINC00511 of. The results confirmed that, LINC00511 can promote the proliferation of liver cancer cell migration and invasion and EMT process. Therefore, we believe: LINC00511 upregulated in HCC causes liver cancer cells get stronger proliferation, migration and invasion. But LINC00511 up-regulated in HCC causes and downstream effector mechanisms is unclear, pending further study.

And its expression level was significantly related to TNM staging, postoperative recurrence and metastasis. Kaplan-Meier survival analysis showed that the total postoperative survival time of patients with high expression LINC00511 was significantly lower than that of low-expression patients, consistent with the TCGA database results. The above results show that LINC00511 may be used as a cancer-promoting factor to affect the occurrence, development and prognosis of HCC, and can be used as a new candidate marker for post-prognostic evaluation after the removal of entotic liver cancer.<BR>To illustrate the relationship between LINC00511 and HCC biological function, we constructed a model of liver cancer cells of transient silent LIN00511. Results have shown that LINC00511 can promote the proliferation, migration, invasive ness and EMT process of liver cancer cells. Therefore, we believe that: LINC00511 in HCC expression increased to promote liver cancer cells to obtain a strong proliferation, migration and invasion capacity. However, the reasons for THE uplift of LINC00511 in HCC and the mechanism of downstream effect are not clear, and need further study.

The expression level of TNM was significantly correlated with TNM stage, postoperative recurrence and metastasis. Kaplan Meier survival analysis showed that the total survival time of patients with high expression of linc00511 was significantly lower than that of patients with low expression, which was consistent with the results of TCGA database. The above results indicate that linc00511 may be used as a tumor promoting factor to influence the occurrence, development and prognosis of HCC, and may be a new candidate marker for the prognosis evaluation after radical hepatectomy.<BR>In order to elucidate the relationship between linc00511 and the biological function of HCC, we constructed a liver cancer cell model of transient silencing linc00511. The results showed that linc00511 could promote the proliferation, migration, invasion and EMT of HCC cells. Therefore, we believe that the up-regulation of linc00511 in HCC promotes the proliferation, migration and invasion of HCC cells. However, the reason for the up regulation of linc00511 in HCC and the mechanism of its downstream effect are not clear and need further study.<BR>