To explore the effect of comprehensive nursing intervention combined with hemodialysis in the treatment of refractory heart failure. The subjects were 43 patients with refractory heart failure treated by comprehensive nursing intervention and hemodialysis from July 2017 to December 2018, including 12 patients with heart valve disease, 11 patients with coronary heart disease, 9 patients with hypertension heart disease, 6 patients with dilated heart disease, 5 patients with pulmonary heart disease, all of which had grade IV cardiac function (NYHA grade). After one month of treatment, the patients' heart function grade, anxiety and depression score, left ventricular end diastolic diameter, left ventricular end systolic diameter, left ventricular ejection fraction, B-type natriuretic peptide were significantly improved (P<br>
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