The obtained drug and 70% ethanol were added to a flat-bottomed flask in an amount of 40: 1, fitted with a reflow condenser and heated under reflow at 70°C. After 30 min, the residue was filtered and the filtrate was collected. The residue was re-placed in a flatbottomed flask and reflowed for 3 times. The filtrates were combined, concentrated under reduced pressure, lyophilized in vacuo, the total flavonoids of jujube were obtained .