In renin - blood vessel tense eleme

In renin - blood vessel tense element - aldosterone system (RAAS), renin catalysis blood vessel anxious usually original (one kind of non-active intermediate) formation. The blood vessel tight element is originally its only substrate. Therefore, suppression renin activeness may prevent RAAS the regulating process, thus reduces the blood vessel anxiously usually original I, blood vessel anxious usually original II and aldosterone level, then causes the vasodilatation, Shui Hena to output the increase as well as the blood pressure reduces. Because the renin has the sole function in vivo, therefore the renin inhibitor responds not good relatively small, and not too possibly occurs coughs without expectorating and so on to respond not good. This is similar in ACEI causes responded not good.