The R2R3 MYB genes identified in th

The R2R3 MYB genes identified in the long arm of chromosome 10, where Aft was mapped (Sapir et al.,702008), encode proteins which are phylogenetically correlated with many other plant MYBs involved in anthocyanin synthesis (Figure 1D). They also show very similar sequences: the R2/R3 MYB domains, which specify DNA binding (Lin-Wang et al., 2010), are highly conserved, whereas the C-terminal regions, which influence the strength of the promoter activation (Heppel et al., 2013), are more variable (Supplemental Figure 1). In Aft, the four R2R3 MYB genes show sequence polymorphisms compared to the WTcounterparts, which produce amino acid variants in the relative polypeptides