A plain abdominal radiograph, inclu

A plain abdominal radiograph, including the kidneys, ureters, and bladder, is also recommended in the primary assessment. After the identification of a mass on x‐ray, a renal/bladder sonogram should be performed. This noninvasive imaging modality allows for a more thorough diagnostic evaluation. The laterality of the mass, its size, and the presence of calcifications are observed by abdominal CT. MRI may provide information regarding invasion into regional lymph nodes and vessels. Bone scintigraphy and/or a skeletal survey are often helpful when bone metastasis is suspected [1].The histopathological examination of neuroblastoma reveals a tumor with undifferentiated, primitive‐appearing round blue cells with hyperchromatic nuclei and scant cytoplasm in a lobular pattern. Sheets of Homer‐Wright pseudorosettes, consisting of neuroblasts surrounding eosinophilic neuropil, are a pathognomonic feature confirming the diagnosis of neuroblastoma [5–7].Shimada et al. [8] developed a classification scheme for neuroblastomas. The system uses the degree of neuroblast differentiation, the Schwannian stromal quality, the MKI, the growth pattern, and the patient's age to classify the histology as either favorable or unfavorable. Patients belonging to one of the three following categories are considered within the favorable category: