本课题前期开展了硝苯地平治疗冻疮实验的药效学研究，采用-20℃的95%

This paper studies conducted preliminary pharmacodynamics of nifedipine frostbite experiments, the use of 95% ethanol processing frozen -20 ℃ frostbite model study of nifedipine in SD rats after the right hind established treatment for frostbite, experiment the results showed that nifedipine can effectively reduce inflammation in rats with frostbite, the skin tissue damage can be repaired, play a therapeutic effect.

Prior to this topic, a pharmacological efficacy study of the experiment of nitrobenzene to treat frostbite was carried out, and the frozen sore model established after the right foot of the sage-frozen treatment of SD rats with 95% ethanol freezing treatment of -20 degrees C examined the therapeutic effect of nitrobenzene flat on frostbite, and the experimental results showed that nitrobenzene can effectively relieve the inflammation of frostbite rats and repair the damaged skin tissue. Play a certain therapeutic effect.

In the early stage of this project, the pharmacodynamics of nifedipine in the treatment of frostbite was studied. The frostbite model of SD rats was established after the right hind foot was frozen with - 20 ℃ 95% ethanol to investigate the therapeutic effect of nifedipine on frostbite. The experimental results show that nifedipine can effectively alleviate the inflammation of frostbite rats, repair the damaged skin tissue and play a certain therapeutic effect.