亚急性和慢性毒性：亚急性毒性：口服：含NMP的食物以1%的浓度喂给小鼠

Subacute and chronic toxicity: <br>Subacute toxicity: <br>Oral: foods containing NMP at a concentration of 1% of fed mice, rats and dogs for 90 days feeding. In the animal experiments toxin potency NMP were found. <br>Skin: The daily amount of 0.4-0.8mg / kg of NMP to make contact with the skin test in rabbits for 20 days. In the animal experiments toxin potency NMP were found. <br>Inhalation: respectively, and 1.0mg / l concentration 0,0.1,0.5, 6 hours per day, 5 days per week the rats were placed in NMP aerosol vapor mixture, for 4 weeks. Placed in the test was found at a concentration of 1.0mg / l of dyspnea and lethargy rats excess mortality. <br>Chronic toxicity: <br>6 hours, 5 days per week day, rats are placed in the atmospheric concentration of 0.04 or 0.4mg / L for 2 years in, shortened life expectancy was not observed toxicity or carcinogenic potency.

Subacute and chronic toxicity:<br>Subacute toxicity: Oral: Food containing NMP was fed to mice, rats and dogs at a concentration of 1% for 90 days.<br>The toxin effect of NMP was not found in the above-mentioned animal experiments. Skin: NMP and skin contact experiments on rabbits at 0.4-0.8 mg/kg per day for 20 days.<br>The toxin effect of NMP was not found in the above-mentioned animal experiments. Inhalation: 0, 0.1, 0.5 and 1.0 mg/l concentrations, respectively, 6 hours per day, 5 days a week to put rats in the NMP aerosol steam mixture for 4 weeks.<br>Drowsy breathing difficulties and excessive mortality were found in rat tests with concentrations of 1.0 mg/l.<br> Slow toxicity: Rats were placed at atmospheric concentrations of 0.04 or 0.4 mg/L for 2 years for 6 hours, 5 days a week, with no short life toxicity or carcinogenic effects observed.

Subacute and chronic toxicity:<br>Subacute toxicity:<br>Oral administration: NMP-containing foods were fed to mice, rats and dogs at a concentration of 1% for 90 days. No toxic effect of NMP was found in the above animal experiments.<br>Skin: Rabbits were exposed to NMP at a daily dose of 0.4-0.8 mg/kg for 20 days. No toxic effect of NMP was found in the above animal experiments.<br>Inhalation: Rats were exposed to NMP aerosol vapor mixture at concentrations of 0, 0.1, 0.5 and 1.0 mg/l, 6 hours a day and 5 days a week for 4 weeks. Sleeping dyspnea and excessive mortality were found in rats exposed to 1.0 mg/l concentration.<br>Chronic toxicity:<br>Rats were exposed to atmospheric concentration of 0.04 or 0.4 mg/L for 2 years, 6 hours a day and 5 days a week. No toxicity or carcinogenic effect of shortening life span was observed.<br>