Other oral alternatives include dox

Other oral alternatives include doxycycline and the fluoroquinolones, which when dictated by cultures and sensitivities, may be used safely in children. 1ntravenous antimicrobials with activity against mixed flora such as ß-lactam/ß-lactamase inhibitor combinations, TMP/SMX plus clindamycin, and secondgeneration cephalosporins with anaerobic activity (e.g., cefoxitin) are suitable empiric choices for severe infections (References 56, 62). Broad-spectrum carbapenems should be reserved for treatment failure or drug-resistant isolates.Therapy duration will vary by the severity of injury, but it can range from 7-14 days for soft tissue infections to 3-6 weeks for involvement of the joints or bones