骨质疏松症一种多发于绝经后妇女的骨代谢性疾病，因其易导致骨质疏松性骨折

骨质疏松症一种多发于绝经后妇女的骨代谢性疾病，因其易导致骨质疏松性骨折严重影响患者的生活质量而受到广泛重视。成骨细胞介导的骨生成与破骨细胞介导的骨吸收之间的失衡是骨质疏松的重要成因。大量研究表明，长非编码RNA（LncRNA）在表观、转录等水平参与调控成骨细胞和破骨细胞的分化与功能等过程，影响骨质疏松OP的发生发展。本文对LncRNA调节成骨和破骨细胞的分化及功能的作用进行综述，旨在为骨质疏松的防治提供新的思路。

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Osteoporosis is a bone metabolic disease that occurs frequently in postmenopausal women. It is widely valued because it can cause osteoporotic fractures and seriously affect the quality of life of patients. The imbalance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption is an important cause of osteoporosis. A large number of studies have shown that long non-coding RNA (LncRNA) participates in the process of regulating the differentiation and function of osteoblasts and osteoclasts at the level of appearance and transcription, and affects the occurrence and development of osteoporotic OP. This article reviews the role of LncRNA in regulating the differentiation and function of osteoblasts and osteoclasts, aiming to provide new ideas for the prevention and treatment of osteoporosis.

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结果 (英语) 2:[复制]

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Osteoporosis, a metabolic bone disease that is common in post-menopaoseal women, is widely valued because it can easily lead to osteoporosis fractures that seriously affect the quality of life of patients. The imbalance between osteoblast-mediated bone production and bone absorption mediated by bone-breaking cells is an important cause of osteoporosis. Numerous studies have shown that long non-coding RNA (LncRNA) is involved in the process of regulating the differentiation and function of osteoblasts and bone-breaking cells at the osteoporosis and transcription levels, affecting the development of osteoporosis OP. In this paper, the role of LncRNA in regulating the differentiation and function of bone and bone-breaking cells is reviewed, with the aim of providing new ideas for the prevention and treatment of osteoporosis.

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结果 (英语) 3:[复制]

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Osteoporosis is a kind of bone metabolic disease in postmenopausal women, because it is easy to lead to osteoporotic fractures, and seriously affects the quality of life of patients. The imbalance between osteoblast mediated osteogenesis and osteoclast mediated bone resorption is an important cause of osteoporosis. A large number of studies have shown that long non coding RNA (lncrna) is involved in the regulation of the differentiation and function of osteoblasts and osteoclasts at the apparent and transcriptional levels, which affects the occurrence and development of osteoporosis. This article reviews the role of lncrna in regulating the differentiation and function of osteoblasts and osteoclasts in order to provide new ideas for the prevention and treatment of osteoporosis.<br>

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