The purpose of this review is to summarize the current knowledge about the role of gut microbiota composition in the development, course, and prognosis of selected neurological
diseases. Global incidence of a number of common neurological disorders is rapidly increasing (Bengmark 2013) and consumption of industrially manipulated meat, dairy and wheat products, which lead to changes in gut microbiota, could be contributing factors (Bengmark 2007). Understanding the efects of diet on human gut microbiota is therefore of major importance (Kau et al. 2011)。
The central nervous system (CNS) and the gut microbiota interact in a bidirectional manner, e.g. the CNS modulates gut functioning in response to psychological and physical
stressors afecting motility, secretion and immune reactivity (Mayer 2000), whereas changes in gut microbiota may cause behavioural and neurochemical changes (Bravo et al. 2011).
Consequently, the term microbiota–gut–brain (MGB) axis was proposed to stress the mportance of these interactions (Collins et al. 2012; Rhee et al. 2009). the MGB regulates
the gastrointestinal (GI) tract and CNS (Dinan et al. 2014) by
The purpose of this review is to summarize the current knowledge about the role of gut microbiota composition in the development, course, and prognosis of selected neurological<br>diseases. Global incidence of a number of common neurological disorders is rapidly increasing (Bengmark 2013) and consumption of industrially manipulated meat, dairy and wheat products, which lead to changes in gut microbiota, could be contributing factors (Bengmark 2007). Understanding the efects of diet on human gut microbiota is therefore of major importance (Kau et al. 2011)。<br><br>The central nervous system (CNS) and the gut microbiota interact in a bidirectional manner, e.g. the CNS modulates gut functioning in response to psychological and physical<br>应激afecting运动,分泌和免疫反应性(迈耶2000),而在肠道菌群的变化可能导致行为和神经化学的变化(Bravo等人,2011)。<br>因此,术语微生物群-肠-脑(MGB)轴被建议将强调这些相互作用的mportance(Collins等人2012; Rhee等人2009)。该MGB调节<br>胃肠(GI)道和中枢神经系统(迪南等人2014)由
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