鬼针草黄酮提取自鬼针草，具有改善降低糖尿病小鼠血糖的作用。黄桂红等进一

Flavonoids extracted from Bidens Bidens having improved reduced blood glucose in diabetic mice. Further studies Huanggui Hong et show Bidens flavonoids can significantly improve palmitate + insulin and induced Hep G2 cells in the IR state, which may be related through upregulation PI3Kp85 mRNA expression, increased GLUT4 mRNA and protein expression of the AKT1 insulin signaling reducing the negative feedback regulation, activation of PI3K / Akt pathway

Ghost needle grass flavonoidextractfrom the ghost needle grass has the effect of improving the blood sugar of diabetic mice. Further studies such as Huang Guihong have shown that the mechanism of hep G2 cell IR, which can be significantly improved by palmitic acid and insulin combined induction, may be related to the reduction of negative feedback regulation of AKT1 to insulin signaling by increasing PI3Kp85 mRNA expression, increasing GLUT4 mRNA and protein expression, and reducing the negative feedback regulation of AKT1 to insulin signaling, activating the PI3K/Akt pathway.

The flavone of Bidens bipinnata is extracted from Bidens bipinnata, which has the effect of improving the blood sugar of diabetic mice. Huang Guihong et al. Further study showed that Bidens bipinnata flavone can significantly improve the IR state of HepG2 cells induced by palmitic acid and insulin, and its mechanism may be related to its ability to up regulate the expression of pi3kp85 mRNA, increase the expression of GLUT4 mRNA and protein, reduce the negative feedback regulation of AKT1 on insulin signal transduction, and activate the PI3K / Akt pathway