Termination of the study was decided after approximately 28 lunar months or 109-111 weeks when mortality was about 50% in the control group and the low dose group of both males and females.When mortality rate(dead or sacrificed animals)in the dosed groups was compared with that of the control group(see pages R 1.3 - R 1.5), the following was noted:Trend analysis did not reveal a positive dose related trend in mortality rate Intergroup comparison, using the Chi-square test, showed a significantly(p