This study presents limited evidence from four individual RCTs that TAC is more effective than verapamil in improving scar pliability and vascularity in keloids and hypertrophic scars after 3 weeks of treatment. However,verapamil has fewer adverse drug reactions compared with TAC, allowing for a longer treatment period and the possibility of effectiveness in patients who cannot receive TAC. Studies with a longer follow-up period and those investigating the combination of verapamil with other therapeutic methods could be considered to better understand the treatment efficacy of verapamil for keloids and hypertrophic scars in the short and long term.•