Abstract: This paper mainly discusses and analyzes the effect of holistic nursing mode in dermatology nursing. Select part of the patients who come to our hospital dermatology department for treatment, select their clinical data as the research object, and randomly divide them into the experimental group and the control group, the average number of the two groups equal, the control group received routine nursing service, the experimental group received holistic nursing scheme, to analyze and discuss the nursing effect of the two groups of patients. Results after systematic treatment and nursing, the two groups of patients have had a significant effect, the experimental group of patients with nursing satisfaction was 96%, the control group of patients with nursing satisfaction was 76%. The difference between the two groups was obvious, with statistical significance. Therefore, it is concluded that the holistic nursing mode for patients in dermatology department can ensure that the nursing content is more perfect and the service effect is better, which is worthy of promotion in the future clinical nursing work.<br>
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