An overview is presented on the global human usage of unconventional animal species (ungulates, rodents, rabbits and hares, kangaroos, reptiles and bats) derived either from wild harvesting or farming • The nutritional value of these species is discussed, focusing on their potential to contribute to food security and to address the protein requirements of a growing population. • The challenges and opportunities arising from the commercial use of these animals are highlighted, as are the problems faced with overexploitation of certain wild species. • Of the species addressed, the rodents appear to present great potential for becoming large commercial commodities for food use.