The results of the present study demonstrate that simulateddirected-learning with a life education intervention developsmeaning of life,[47] positive beliefs,[48] and well-being,[46,49,50]and augments physical, psychological, spiritual, and social healtheducation and promotion among nursing students for animproved quality of life. The quality of simulation activities innursing education augments nursing students’ clinical skills,[51,52]self-efficacy and critical thinking skills,[53] and provides animproved quality of life to many patients in clinical settings.Furthermore, a situation simulation is used for problem-solvingin daily life[54] that is related to teaching and learning processesfor nursing students to learn health education and promotion in anursing education course. The strategy of situated simulationaims to improve nursing students’ handling of stress and fear inclinical practice and to increase professional skills.[55] The specialsimulation is to provide the same quality end-of-life educationand life experiences for nursing students in health education andpromotion.[56] Therefore, simulated directed-learning materialswith many situations for nursing students in a health educationcourse aimed to continue to train nursing students on an elearning platform with a life-education intervention on themeaning of life, positive beliefs, and well-being for a better qualityof life