Data requirements for submissionOn submission of a manuscript authors should provide all data required to understand and verify the research presented in the article; these should be submitted in the following ways. • X-Ray crystallographic data and macromolecular structure and sequence data should be deposited in an appropriate repository. Full requirements for these data types are available below. • All other required data should be submitted as electronic supplementary information. Details of specific data requirements for a journal can be found in the journal specific information.