During operation, polymer electrolyte membrane fuel cell can meet several defects such as liquid water accumulation in gas diffusion layers (GDL) that obstruct the gas to attain the catalyst sites [2]. Yet, the correct function of a PEMFC is assured just if the membrane watercontent ranges between reasonably determinate confines. It is therefore necessary to control well the processes occurring in the fuel cell and to make sure that the production of exact water is sufficient for an excellent membrane hydration, without possibility of flooding. The performances of the PEMFC system are additionally linked to many others parameters, touching the operating conditions, which can be studied by a suitable simulation procedure.