Respiration is controlled voluntarily and involuntarily through the motor and premotor cortex, brainstem, and cervical phrenic nucleus and nerve, involving sensors and autonomic system as well.7 It is not clear how DBS controls respiratory dyskinesia, though it most likely involves stimulating the basal ganglia loop (as it does for limb/trunk dyskinesia) and possibly the thalamic-hypothalamic connections and hypothalamic autonomic system as well, thus influencing both voluntary and involuntary respiration.6,7 It is not clear why only the respiratory muscles were involved. We did not perform the needle EMG study to characterize the underlying physiology for fear of complications, such as pneumothorax due to the perforation of the needle through the diaphragm during dyskinesia. This case will help manage this probably underrecognized and undertreated respiratory dyskinesia in patients withPD in the future.
Respiration is controlled voluntarily and involuntarily through the motor and premotor cortex, brainstem, and cervical phrenic nucleus and nerve, involving sensors and autonomic system as well.7 It is not clear how DBS controls respiratory dyskinesia, though it most likely involves stimulating the basal ganglia loop (as it does for limb/trunk dyskinesia) and possibly the thalamic-hypothalamic connections and hypothalamic autonomic system as well, thus influencing both voluntary and involuntary respiration.6,7 It is not clear why only the respiratory muscles were involved. We did not perform the needle EMG study to characterize the underlying physiology for fear of complications, such as pneumothorax due to the perforation of the needle through the diaphragm during dyskinesia.This case will help manage this probably underrecognized and undertreated respiratory dyskinesia in patients with<br>PD in the future.
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