Their cytotoxic activities were evaluated against six human cancer (HeLa, HepG2, SGC7901, MDA231, HL60, and Lewis) cell lines in vitro using MTT assay. As a result, two triterpenoid saponins showed potent cytotoxic activities against six tumors cell lines and with broad spectrum activities against six human cancer, with IC50 values from 8.40 to 24.39 μM. The cytotoxic activities of 2 are more potent.