In this paper, by bonding the reactant to the electrode, the electrode becomes a functional group with adjustable induction effect, thereby changing the chemical reactivity of the molecule, which is very similar to the induction effect of the traditional functional group. Most importantly, this method can also continuously adjust the electrical properties of the molecule. Using this "electric induction effect", the author realized the base-catalyzed saponification reaction of benzoate, Suzuki-Miyaura cross-coupling reaction, and the rate adjustment of the two-step carboxylic acid amidation reaction. However, the disadvantage is that the target molecule must be connected to the surface of the gold electrode through a sulfhydryl group, which may limit the scope of application of this strategy and the prospect of large-scale application.
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