All the hospitals we work with have good working relationship with PI. We have done maternal and child studies with them. The hospital health information system (HIS) will provide detailed information about general information, laboratory test, GDM screening, and final maternal outcomes.Expected difficulties The most difficulty in this project is whether the pregnant women would regularly check up in the same hospital until deliveries and the cost of medical test. However, this project does not increase extra medical check-ups and cost. So women w can “tolerate”.