实验证明抑制MiR-27a可以通过靶向Toll样受体4(TLR4)刺激

Experiments demonstrate that inhibition of MiR-27a can be involved in stimulating the production of TNF-α and IL-1β as well as pro-inflammatory proteins including cyclooxygenase 2 and inducible nitric oxide synthase by targeting Toll-like receptor 4 (TLR4) Inflammatory response to DR [51] (see Table 2).

Experiments have shown that inhibition of mir-27a can stimulate TNF by targeting toll like receptor 4 (TLR4)- α And IL-1 β And the production of pro-inflammatory proteins including cyclooxygenase 2 and inducible nitric oxide synthase, which are involved in the inflammatory response of Dr [51] (see Table 2).

Experiments have proved that inhibiting MiR-27a can stimulate the production of TNF-α and IL-1β and pro-inflammatory proteins including cyclooxygenase-2 and inducible nitric oxide synthase by targeting Toll-like receptor 4(TLR4), thus participating in the inflammatory reaction of DR [51] (see Table 2).