During pregnancy, the female body will produce certain physiological changes, the blood is in the state of hypercoagulation, and the compensatory fibrinolysis system will be started at the same time, which is helpful for postpartum rapid hemostasis and clearing of venous thrombosis. However, the abnormal increase of D-dimer will lead to the adverse pregnancy outcome, and the serious cases will threaten the lives of mothers and infants. Therefore, as a noninvasive and radiation-free index of thrombosis, D-dimer can dynamically monitor its changes and establish a suitable reference range for pregnancy, which has a guiding role in clinical diagnosis and timely treatment.<br>
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