In order to adapt to the market requirements in the new environment and meet the interests of consumers to the greatest extent, this paper discusses the basic background of Internet marketing, and explores the appropriate marketing channels for pharmaceutical enterprises, namely Internet marketing, to reduce the cost of drug circulation by integrating their own characteristics and development direction. However, the emergence of the new drug online market is a challenge to the marketing concept, marketing means and organizational structure of traditional enterprises. With the development of network technology, especially the establishment of Internet and the formation of enterprise internal network system, network economy gradually plays an important role in the development of world economy. As a new marketing mode, drug Internet marketing, a new term based on the Internet, runs through the whole process of drug enterprises' online operation.