In the process of cell formation in porous materials, firstly, the gas generated by the reaction nucleates in the liquid phase interface, i.e. a large number of gas molecules generated by the reaction are accumulated in the liquid phase interface under the action of unstable thermodynamics. With the increasing amount of gas in the liquid phase, the energy in the liquid phase is supersaturated, while the formation of bubbles in the liquid phase makes the energy in the liquid phase lower. The overall number and distribution of bubble nucleation ultimately affect the morphology of the entire interface, especially the pore size of the largest pores, which will have a greater impact on some physical properties of porous materials such as volume density and porosity. Therefore, the nucleation process of bubbles in the liquid phase interface is deeply discussed, the key factors affecting the pore size structure are analyzed, the effective control of the pore size and morphology is realized, and porous structural materials meeting different purposes are prepared.