The initial strong knockdown effffect was masking another very important property in the biological mode of action of this chemical. It was demonstrated that flflupyradifurone inhibits feeding of adult whiteflflies and the persistence of this effffect is nicely correlated with the observed long-lasting residual effiffiffi-cacy of flflupyradifurone against B. tabaci MED when applied at recommended rates. It is therefore suggested that due to quick feeding cessation after oral uptake of small amounts of foliarly penetrated flflupyradifurone, virus transmission is prevented over a long period of time, signifificantly exceeding the residual effiffifficacy observed with thiamethoxam. This confifirms the results of other studies of B. tabaci MEAM1 where flflupyradifurone when tested for its residual effiffifficacy outcompeted other systemic insecticides such as cyantraniliprole, sulfoxaflflor and pymetrozine.