放射性碘在唾液腺、泪腺和胃肠道(包括胃粘膜和结肠)的积聚是甲状腺切除术

The accumulation of radioactive iodine in the salivary glands, lacrimal glands, and gastrointestinal tract (including gastric mucosa and colon) is a common finding during whole-body scintigraphy in patients with thyroid cancer after thyroidectomy (103), and may be in some doses associated with radioactive iodine therapy. Play a role in related side effects (104). In salivary glands and lacrimal glands, NIS protein was detected in the basolateral membrane of all ductal epithelial cells (105, 106). Similarly, NIS immune responses were detected in the basolateral membrane of gastric mucosal mucosal epithelial cells and the basolateral membrane of the inner epithelial cells of colonic mucosal mucosa crypts (106). This indicates that NIS is involved in the active transport of iodine from the serum to these exocrine glands, and the pathogenesis of saliva, tears and gastrointestinal dysfunction after radioactive iodine treatment

The accumulation of radioactive iodine in the salivary glands, tear glands and gastrointestinal tract (including the stomach mucous membranes and colon) is a common finding in patients with thyroid cancer after thyroid removal (103) and may play a role in some dose-related side effects associated with radioactive iodine therapy (104). In the salivary glands and tear glands, NIS proteins were detected in the outer membrane of the substrate of all catheter epithyl cells (105,106). Similarly, a NIS immune response (106) was detected in the substrate outer membrane of the stomach mucous membrane mucous protein deposition epithelyl cells and in the substrate outer membrane of the epitheliosis cells in the colon mucous membrane cryptosphere. This indicates that NIS is involved in the active transport of iodine from serum to these exocrine gland secretions, as well as the pathogenesis of saliva, tears and gastrointestinal dysfunction after radiation iodine treatment

The accumulation of radioiodine in salivary gland, lacrimal gland and gastrointestinal tract (including gastric mucosa and colon) is a common finding in patients with thyroid cancer after thyroidectomy (103), and may play a role in some dose-related side effects associated with radioiodine therapy (104). NIS protein was detected in the basolateral membrane of all ductal epithelial cells (105106) in salivary gland and lacrimal gland. Similarly, NIS immunoreactivity was detected in the basolateral membrane of gastric mucin deposition epithelial cells and the basolateral membrane of colonic crypt inner epithelial cells (106). These results indicate that NIS is involved in the active transport of iodine from serum to the secretion of these exocrine glands, and the pathogenesis of salivary, tear and gastrointestinal dysfunction after radioiodine treatment<br>