药效动力学遵循开放式模型的一级动力学。分布相半衰期和消除相半衰期分别为

The pharmacodynamics follows the first-order kinetics of the open model. The distribution phase half-life and elimination phase half-life are 10-15 minutes and 60-100 minutes respectively. The apparent volume of distribution is small, which is equivalent to the volume of extracellular fluid. The overall clearance and renal clearance are 170ml / min and 130ml / min, respectively

Pharmacokinetics follows the primary kinetics of open models. Distribution phase half-life and elimination phase half-life are 10 to 15 minutes and 60 to 100 minutes, respectively. The apparent distribution volume is small, which is equivalent to the accumulation of extracellular liquid. Overall clearance and kidney removal rates of 170ml/min and 130ml/min, respectively

The pharmacodynamics follows the first-order dynamics of the open model. The half-life of distribution phase and elimination phase are 10-15 minutes and 60-100 minutes respectively. The apparent distribution volume is smaller, which is equivalent to the volume of extracellular fluid. The overall clearance rate and renal clearance rate were 170 ml / min and 130 ml / min respectively<br>