According to this, the developments of new strategies for enhancing the protection of the steel is highly relevant, or even the direct synthesis of the catalyst over the surface of the metallic substrate of the structured. Furthermore, it is important designing specific experiments to establish the role and contribution of every possible component of the feed-streams during the degradation processes of the steel coated with the catalyst. Besides, this may be complemented with the use of other alloys or metallic substrates. Equally important is to carry out several long-term experiments for collecting enough information about the chemical and physical transformations of these kind of devices submitted to certain atmospheres, in order to be able of develop microreactors forspecific reactions with an estimated lifetime. Finally, although the use of sulfur compounds may be easily dodged in every step of the experimental setup, the postmortemcharacterization of the microreactor MR300 allowed reaffirming the relevance of avoiding the presence of any compound containing sulfur for these applications because the chemical transformation into stable species in both the catalyst and the steel, may promote loss of activity of the active sites where metallic cations are involved. In addition, the degradation of the material of the microreactor may produce the weakening of the joining between microreactor and catalyst.