目前已经有研究证实 Coats 病患者眼内 VEGF 浓度明显升高[1

At present, studies have confirmed that the concentration of VEGF in the eyes of Coats disease patients is significantly increased [13], and there are reports in the literature that the VEGF concentration in the eyes of patients with Coats disease, such as the anterior chamber, vitreous body, and subretinal space, has increased [14]. Injecting anti-VEGF drugs into the body cavity is to reduce the concentration of VEGF, and then stabilize or degenerate abnormal blood vessels, promote the absorption of subretinal fluid and exudate. There are clinical data reported that anti-VEGF drugs are effective in treating Coats disease

Studies have confirmed a significant increase in VEGF concentration in the eyes of Coats patients, there are literature reports that many parts of Coats patients, such as the front room, glass body, lower retinal cavity liquid seismostaly found THAT VEGF is elevated, the glass cavity injection anti-VEGF drug is by reducing the VEGF concentration, and then stabilize or degenerate abnormal blood vessels, promote the absorption of sub-retina fluid and osmosis, there are reports of effective veGF drug treatment.

At present, studies have confirmed that the concentration of VEGF in the eyes of Coats disease patients is significantly increased [13]. It has been reported that VEGF levels are increased in many parts of the eyes of coats patients, such as anterior chamber, vitreous body and subretinal cavity [14]. Intravitreal injection of anti VEGF drugs is to reduce the concentration of VEGF, It can stabilize or degenerate abnormal blood vessels and promote the absorption of subretinal effusion and exudation<br>