Microarray ResultsThe microarray revealed altered levels of expression in 70 miRNAs between HIE and control samples.Of these, 67 miRNAs were downregulated, and 3 miRNA were upregulated in the HIE group. Figure 1 (available at www.jpeds.com) displays the log fold change in expression of the 70 miRNA. Hsa-miR-374a had the greatest expression change, being significantly downregulated in HIE vs control infants (log fold change of 2.231, P < .001). No miRNA data from the microarray results had a statistically significant change in expression between the HIE and perinatal asphyxia group, or between the perinatal asphyxia and control groups.