Marine actinomycetes are abundant in species and widely inhabit the surface and body of marine animals and plants, as well as the sediments and seawater. Studies have shown that the diversity of separable marine actinomycetes is closely related to the sources and their ecological and geographical environment. For example, compared with other sources, the actinomycetes isolated from marine animals and plants have higher species diversity [3]. As the diversity of metabolites is closely related to biodiversity, the potential for obtaining abundant and novel secondary metabolites from actinomyces associated with the marine host is relatively high. At present, the episymbiotic actinomycetes isolated are mainly from marine invertebrates such as sponges, ascidians, and corals, as well as algae such as brown algae, etc. Similar to the actinomycetes from sediments, the proportion of actinomycetes associated with marine animals and plants is the highest in Streptomyces, followed by Micromonospora.