Endomembrane protein trafficking has emerged as important means of regulating stress responses inplants. The Arabidopsis SNX1 protein is involved in recycling the iron transporter IRT1, thus promoting itspresence at the plasma membrane. SNX1 and its interacting partners undergo stress-related regulation atboth transcriptional and posttranslational level, which may include differential regulation at tissue level.Based on this, we explore the tissue-specific regulation of iron import, specifically concentrating on thefactors involved in the expression and recycling of IRT1 in root tissues. We propose that differentprocesses affecting IRT1 regulation may lead to similar outcomes, allowing for fine-tuning iron acquisitionand distribution.