由于细胞接种在不同间距与面积的粘附小岛上，导致MC3T3-E1细胞圆度

Since the cells are seeded on a different area of ​​the adhesive island spacing, resulting in lower roundness of MC3T3-E1 cells, cell spreading morphology quite different, so the arrangement direction F-actin intracellular more messy, resulting in a higher error bar in Fig 3F .

Because the cell inoculation inoculates on the adhesion of different spacing and area, resulting in a decrease in the roundness of MC3T3-E1 cells, and a large difference in cell spread morphology, the direction of f-actin arrangement in the cell is more cluttered, resulting in a higher error bar of Fig 3F.

The roundness of MC3T3-E1 cells was reduced and the spread of cells was different because of cell inoculation on the adhesion islands with different spacing and area, so the arrangement direction of F-actin in cells was disordered, resulting in higher error bar of fig 3F.