Annexin V ConjugatesAnnexin V is a

Annexin V ConjugatesAnnexin V is a 35-36 kDa protein that has a high affinity for phosphatidylserine (PS). During apoptosis, PS is translocated from the inner to the outer leafletof the plasma membrane, where it can be stained by fluorescent conjugates of Annexin V, for detection of apoptotic cells by flow cytometry (Figure 1) orfluorescence microscopy. Biotium offers Annexin V conjugates and kits featuring our exceptionally bright and photostable CF® dyes. For example, our CF®488A green fluorescent Annexin V conjugate is much brighter and more photostable than the traditional FITC-Annexin V, allowing the use of 10-fold less conjugate in staining. Our near-infrared CF® dye conjugates of Annexin V are supplied lyophilized and preservative-free, and are suitable for in vivo imaging.