前列腺素是导致疼痛的重要炎性介质之一,前列腺素的增多也会加剧缓激肽等炎

Prostaglandins are important inflammatory mediators leading to pain, pain induced increase effect also exacerbate inflammatory mediators such as bradykinin, prostaglandins, inhibition of prostaglandin bout ointments will analgesic effect (increased prostaglandin would be more sensitive to pain sensors). Histamine is the most important cause itching inflammatory mediators, histamine and prostaglandin may be reduced actuation threshold of itching bout ointment suppressed the increase of prostaglandins may play a role itching.

前列腺素是导致疼痛的重要炎性介质之一,前列腺素的增多也会加剧缓激肽等炎性介质的致疼痛作用，布特软膏抑制前列腺素也就起到镇痛作用(前列腺素的增多会使疼痛感应器更加敏感)。组织胺是导致瘙痒的最主要的炎性介质，前列腺素可以降低组织胺致瘙痒的阈值，布特软膏抑制前列腺素的增多可以起到止痒的作用。

Prostaglandins are one of the important inflammatory mediators that cause pain. The increase of prostaglandins will also aggravate the pain causing effect of inflammatory mediators such as bradykinin. The inhibition of prostaglandins by Bute ointment will also play an analgesic role (the increase of prostaglandins will make pain sensors more sensitive). Histamine is the most important inflammatory mediators of pruritus. Prostaglandins can reduce the threshold of pruritus induced by histamine. Bute ointment can inhibit the increase of prostaglandins and play an anti pruritus role.