Relevance toTraumatic BrainInjury-inducedcognitive deficits1. Although TBI is a potential risk factor of AD and affectivedisorders, currently, it is not clear how TBI-related cognitivedeficits are associated with SCD and AD. 2. SCD is oftenobserved in patients with a history of TBI. 3. People with TBIand AD also share similar pathological alterations. 4. If arelationship between TBI (-related SCD) and dementia canbe established, better diagnosis and early preventionstrategy could be designed to prevent TBI-related SCDand dementia