Distribution of CD8+CD28− T-cellsIn all lymphocyte isolates derived from control PBL, maternal PBL, d. basalis and d. parietalis a clear population of CD3+CD8+CD28− T-cells can be identified (Figure 2a). A significantly higher percentage of CD8+CD28− T-cells is observed in d. parietalis compared to d. basalis in early pregnancy (p < 0.001) and after term pregnancy (p = 0.004) (Figure 2a, b). In addition, a significantly higher percentage of CD8+CD28− T-cells is observed in all decidua samples compared to maternal PBL samples and PBL samples of non-pregnant control donors (all p-values