In addition, it has been proved that apoE can influence the formation of as by influencing gene expression of cells controlled by microRNA. Therefore, apoE knockout mice are more likely to construct as model. ApoE gene was transferred from apoE deficient mice by retrovirus via bone marrow transplantation. It is found that the apolipoprotein E gene can only inhibit AS when it is transposed in foam cell formation stage, but it is not effective in subsequent transposition. Therefore, apolipoprotein E gene can only be used for early treatment of as.<br>
正在翻译中..