After the Cangwu m5.4 earthquake in Guangxi,the Guangxi earthquake emergency mobile command coordination system was researched and constructed, and the WeChat mobile terminal system based on the enterprise public number was mainly researched and developed. This paper introduces the construction of the system and the role it plays in the emergency response of Beiliu m5.2 earthquake, and then analyzes and discusses the upgrading and optimization direction of the mobile command coordination system of earthquake emergency.